New Delhi: A team of researchers from the Indian Institute of Technology (IIT) Delhi has come up with a non-invasive and time-efficient EEG-based brain source localisation framework for epilepsy focal detection.
“Epilepsy is the fourth most common neurological disorder in the world and affects millions worldwide. Quite a lot of epilepsies can be controlled by medicines, however, when medicines fail to control seizures, it is labelled as drug-resistant epilepsy. The complex and tedious task in surgical evaluation is to determine the origin of electrical abnormality and correlate it with a structural abnormality of the brain,” the institute said in a statement on Friday.
The researchers have proposed novel head harmonics-based algorithms for seizure localisation.
Professor Lalan Kumar from the department of electrical engineering, who also led the research said: “We have proposed utilisation of spherical harmonics and head harmonics basis functions for seizure localisation. To the best of our knowledge, this is the first non-invasive and time-efficient seizure localisation attempt considering the comfort of patients.”
Researchers have validated the proposed source localisation algorithms on clinical EEG data for epileptogenic zone localisation. “The proposed framework offers an effective solution to clinicians in automated and time-efficient localisation,” the statement said.
Stressing that structural abnormalities are subtle to be identified in MRI alone, it explained: “Other modalities utilised by neurosurgeons are PET scan, which involves intake of radioactive substances. Even the MEG facility is very limited in India.
Apart from these, there are invasive surgeries that are available. It takes around two-eight hours for epileptogenic zone detection and is usually uncomfortable for patients.”